Table 1

Baseline and Echocardiographic Characteristics According to Tertiles of eas Index

eas Index < 0.08
(n = 75)
0.08 < eas Index < 0.11
(n = 75)
eas Index > 0.11
(n = 75)
p Value
Age, yrs65.6 ± 8.262.7 ± 10.261.4 ± 11.10.0297
Race, white66 (88.0)61 (81.3)62 (82.7)0.4994
Women7 (9.3)11 (14.7)19 (25.3)0.0267
BMI, kg/m228.68 ± 4.3529.27 ± 4.4728.19 ± 4.600.3534
Living arrangements, alone8 (10.7)12 (16.0)14 (18.7)0.3790
Marital status, not married11 (14.7)13 (17.3)26 (34.7)0.0060
Current smoker3 (4.0)11 (14.7)14 (18.7)0.0642
Current medical therapy
 ASA73 (97.3)70 (94.6)72 (97.3)0.5891
 Other antiplatelet agent34 (45.3)36 (48.0)26 (35.1)0.2466
 ACEi48 (64.0)46 (61.3)47 (63.5)0.9373
 ARB11 (14.9)16 (21.3)5 (6.8)0.0395
 Beta-blocker62 (82.7)58 (77.3)65 (87.8)0.2394
 Calcium-channel blocker19 (25.3)18 (24.3)12 (16.2)0.3391
 Statin69 (93.2)66 (89.2)70 (94.6)0.4369
History of MI39 (52.0)31 (41.3)28 (37.3)0.3740
History of CABG29 (38.7)29 (38.7)36 (48.0)0.4085
History of PCI47 (62.7)49 (65.3)47 (62.7)0.9261
History of DM22 (29.3)23 (30.7)18 (24.0)0.6294
History of HTN60 (80.0)58 (77.3)58 (77.3)0.9009
History of hyperlipidemia70 (93.3)71 (94.7)69 (92.0)0.8071
NYHA functional class
 I68 (90.7)70 (93.3)67 (89.3)
 II6 (8.0)4 (5.3)5 (6.7)0.4268
 III1 (1.3)1 (1.3)3 (4.0)
History of depression8 (10.7)9 (12.0)11 (14.7)0.7516
Resting LVEF, %58.5 ± 9.359.0± 8.457.4 ± 9.80.5819
Resting WMSI1.16 ± 0.321.09 ± 0.201.19 ± 0.370.1279
Resting MV deceleration time, ms245.3 ± 63.2225.2 ± 50.7220.0 ± 59.90.0219
Resting E/A ratio0.85 ± 0.241.02 ± 0.281.07 ± 0.38<0.0001
Resting E/e′12.8 ± 4.211.8 ± 4.311.2 ± 4.60.0793
Resting eas index0.07 ± 0.010.09 ± 0.010.14 ± 0.03<0.0001
MSIMI23 (30.7%)30 (40.0)45 (60.0)0.0011

Values are mean ± SD or n (%).

ACEi = angiotensin-converting enzyme inhibitor; ARB = angiotensin receptor blocker; ASA = aspirin; BMI = body mass index; CABG = coronary artery bypass grafting; DM = diabetes mellitus; eas index = (e′/[a′ × s′]); HTN = hypertension; LVEF = left ventricular ejection fraction; MI = myocardial infarction; MSIMI = mental stress–induced myocardial ischemia; MV = mitral valve; NYHA = New York Heart Association; PCI = percutaneous coronary intervention; WMSI = wall motion score index.