Table 3

Clinical and Coronary CTA Univariable Predictors of Events

Combined Adverse CV Events
HR (95% CI)
p ValueCV Death/MI
HR (95% CI)
p Value
Clinical characteristics
 Age1.00 (0.99–1.02)0.331.06 (1.03–1.10)<0.0001
 Male1.01 (0.75–1.36)0.911.44 (0.71–2.89)0.30
 BMI1.02 (1.01–1.03)0.231.05 (1.01–1.08)0.12
 Hypercholesterolemia1.47 (1.15–1.88)0.00181.13 (0.68–1.88)0.63
 Hypertension1.19 (0.92–1.55)0.181.34 (0.74–2.42)0.32
 Family history of CAD0.78 (0.59–1.03)0.080.55 (0.28–1.08)0.08
 Diabetes1.29 (1.01–1.65)0.031.35 (0.80–2.26)0.25
 Smoking0.79 (0.61–1.01)0.060.59 (0.33–1.04)0.06
 Positive stress test1.74 (1.04–2.91)0.032.43 (0.97–6.11)0.05
Medical therapy
 Nitrates1.86 (1.48–2.34)<0.00012.61 (1.57–4.36)0.0002
 Beta-blockers0.99 (0.77–1.26)0.921.63 (0.89–2.98)0.11
 Aspirin1.47 (0.90–2.40)0.112.08 (0.65–6.65)0.21
 Calcium channel blockers0.97 (0.75–1.25)0.820.46 (0.24–0.88)0.01
 ACE-inhibitors1.05 (0.84–1.32)0.641.28 (0.96–1.71)0.08
 AT1 blockers1.20 (0.89–1.64)0.221.57 (0.97–2.54)0.06
 Diuretics1.50 (1.18–1.91)0.00092.75 (1.70–4.45)<0.0001
 Amiodarone1.19 (0.80–1.76)0.381.48 (0.70–3.10)0.29
 Statins1.03 (0.81–1.31)0.760.71 (0.43–1.16)0.17
UCT
 01.001.00
 12.75 (2.06–3.66)<0.00011.24 (0.65–2.35)0.51
 28.39 (6.07–11.61)<0.00017.58 (4.02–14.30)<0.0001
 38.47 (4.57–15.70)<0.000110.19 (2.9–35.43)0.0003
CAPS
 11.001.00
 26.77 (4.7–10.8)<0.00013.71 (1.11–12.36)0.03
 33.09 (2.01–4.73)<0.00013.76 (1.31–10.76)0.01
 412.6 (8.1–19.8)<0.000124.12 (8.35–69.65)<0.0001

CI = confidence interval; HR = hazard ratio; other abbreviations as in Table 1.

  • p < 0.05 versus patients with combined adverse CV events.

  • p < 0.05 versus patients with CV death/MI.