Table 2

Enzyme Release and Cardiac Function

ControlTherapyDifferencep Value
CK, AUC68,840 ± 8,816 (51,094 to 86,587)65,772 ± 7,952 (49,765 to 81,778)3,069 ± 8,001 (–13,037 to 19,174)0.70
Infarct size, % LV
 4 days21.7 ± 2.3 (17.0 to 26.4)15.4 ± 2.1 (11.3 to 19.6)6.3 ± 2.2 (1.9 to 10.7)0.01
 4 months18.6 ± 2.0 (14.5 to 22.7)13.9 ± 1.7 (10.4 to 17.4)4.7 ± 1.9 (0.9 to 8.5)0.02
 12 months16.2 ± 2.2 (11.7 to 20.6)12.5 ± 1.9 (8.7 to 16.3)3.7 ± 2.0 (–0.4 to 7.8)0.08
LVEF, %
 4 days52.2 ± 2.2 (47.8 to 56.7)55.3 ± 1.9 (51.4 to 59.2)–3.1 ± 2.0 (–7.2 to 1.1)0.14
 4 months53.5 ± 2.0 (49.4 to 57.7)53.7 ± 1.8 (50.2 to 57.3)–0.2 ± 1.9 (–4.0 to 3.6)0.92
 12 months49.6 ± 2.7 (44.2 to 55.0)53.6 ± 2.3 (49.0 to 58.2)–4.0 ± 2.4 (–9.0 to 1.0)0.11

Values are mean ± SE (95% confidence intervals) after adjustment for treated artery, time from first symptom to admission, and ST-segment deviation as explained in the methods. The p values are from adjusted linear regression models.

AUC = area under the curve; CK = creatine kinase; LV = left ventricle; LVEF = left ventricular ejection fraction.